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Arch Iran Med. 2020;23(6): 397-402. doi: 10.34172/aim.2020.33

Original Article

Effect of N-acetylcysteine against Vancomycin-Induced Nephrotoxicity: A Randomized Controlled Clinical Trial

Shirinsadat Badri 1,2 ORCID, Rasool Soltani 1 * ORCID, Mina Sayadi 3, Farzin Khorvash 4,5, Mohsen Meidani 4, Shahram Taheri 2

Cited by CrossRef: 12

1- Feng Y, Yang Y, Chen H. Small Molecules as a Source for Acute Kidney Injury Therapy. SSRN Journal. 2021; [Crossref]
2- Karimian A, Karimzadeh I, Shafiekhani M, Heidari R, Masjedi F, Izadi F, Barshan-Tashnizi N, Kane-Gill S, Mahmoudi L. Protective effects of silymarin on preventing vancomycin nephrotoxicity in infectious patients: a randomized, double-blinded, placebo-controlled, pilot clinical trial. Naunyn-Schmiedeberg's Arch Pharmacol. 2024; [Crossref]
3- Bellos I, Pergialiotis V, Perrea D. Kidney biopsy findings in vancomycin-induced acute kidney injury: a pooled analysis. Int Urol Nephrol. 2022;54(1):137 [Crossref]
4- Yuan M, Briscese K, Hong T, Brunetti L. Natural products for the prevention of antibiotic-associated kidney injury. Current Opinion in Toxicology. 2022;32:100363 [Crossref]
5- Magalhães E, Silva B, Aires N, Ribeiro L, Ali A, Cavalcanti M, Nunes J, Sampaio T, de Menezes R, Martins A. (−)-α-Bisabolol as a protective agent against epithelial renal cytotoxicity induced by amphotericin B. Life Sciences. 2022;291:120271 [Crossref]
6- Badri S, Vahdat S, Seirafian S, Pourfarzam M, Gholipur-Shahraki T, Ataei S. Homocysteine-Lowering Interventions in Chronic Kidney Disease. 2021;10(3):114 [Crossref]
7- Hong H, Chen Y, Zhou L, Bao J, Ma J. Risk factors analysis and construction of predictive models for acute kidney injury in overweight patients receiving vancomycin treatment. Expert Opinion on Drug Safety. 2024;:1 [Crossref]
8- Packialakshmi B, Stewart I, Burmeister D, Chung K, Zhou X. Large animal models for translational research in acute kidney injury. Renal Failure. 2020;42(1):1042 [Crossref]
9- Sadeghi H, Karimizadeh E, Sadeghi H, Panahi kokhdan E, Mansourian M, Abbaszadeh-Goudarzi K, Shokripour M, Asfaram A, Doustimotlagh A, Abdel-Daim M. Protective Effects of Hydroalcoholic Extract of Rosa canina Fruit on Vancomycin-Induced Nephrotoxicity in Rats. Journal of Toxicology. 2021;2021:1 [Crossref]
10- Mosayebi S, Soltani R, Shafiee F, Assarzadeh S, Hakamifard A. Evaluation of the Effectiveness of N-Acetylcysteine in the Prevention of Colistin-Induced Nephrotoxicity. 2021;10(4):159 [Crossref]
11- Alosaimy S, Rybak M, Sakoulas G. Understanding vancomycin nephrotoxicity augmented by β-lactams: a synthesis of endosymbiosis, proximal renal tubule mitochondrial metabolism, and β-lactam chemistry. The Lancet Infectious Diseases. 2024;24(3):e179 [Crossref]
12- Feng Y, Yang Y, Chen H. Small molecules as a source for acute kidney injury therapy. Pharmacology & Therapeutics. 2022;237:108169 [Crossref]

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About Us

A Monthly Peer-Reviewed Medical Journal Published by the Academy of Medical Sciences of the I.R. Iran; Indexed in PubMed/MEDLINE, ISI Web of Science, EMBASE, SCOPUS, CINHAL, PASCAL, CSA, SID, ISSN: Print 1029-2977, Online 1735-3947.The impact factor of Archives of Iranian Medicine according to Journal Citation Reports® (JCR®) 2016 is 1.20.