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Arch Iran Med. 2023;26(10): 554-560.
doi: 10.34172/aim.2023.81
PMID: 38310411
PMCID: PMC10862095
Scopus ID: 85184111463
  Abstract View: 1015
  PDF Download: 513

Original Article

Ethnic Disparities in Major Adverse Cardiac and Cerebrovascular Events (MACCEs) and Postoperative Outcomes Following Coronary Artery Bypass in Northeastern Iran (2007–2016)

Mahin Nomali 1,2 ORCID logo, Aryan Ayati 3 ORCID logo, Amirhossein Tayebi 4, Keyvan Moghaddam 5, Soheil Mosallami 6, Gholamali Riahinokandeh 7, Mahdis Nomali 8, Gholamreza Roshandel 9* ORCID logo

1 Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
2 Student Research Committee, Golestan University of Medical Sciences, Gorgan, Iran
3 Tehran Heart Center, Cardiovascular Diseases Research Institute, Tehran University of Medical Sciences, Tehran, Iran
4 Cardiovascular Research Center, Alborz University of Medical Sciences, Karaj, Iran
5 Supervisory Department, Kordkuy Amiralmomenin Hospital, Golestan University of Medical Sciences, Gorgan, Iran
6 Open Heart Intensive Care Unit, Kordkuy Amiralmomenin Hospital, Golestan University of Medical Sciences, Gorgan, Iran
7 Department of Surgery, School of Medicine, Sayyad Shirazi Hospital, Kordkuy Amiralmomenin Hospital, Golestan University of Medical Sciences, Gorgan, Iran
8 Shafa Heart Subspecialty Hospital, Golestan, Gorgan, Iran
9 Golestan Research Center of Gastroenterology and Hepatology, Golestan University of Medical Sciences, Gorgan, Iran
*Corresponding Author: Gholamreza Roshandel, Emails: roshandel_md@yahoo.com; , Email: roshandel@goums.ac.ir

Abstract

Background: Turkmens are an ethnic group mainly living in northeastern Iran. Despite previous studies on coronary artery bypass surgery (CABG) outcomes among different ethnicities, the effect of Turkmen ethnicity on outcomes of CABG surgery is still unknown. We aimed to assess the association between Turkmen ethnicity and postoperative outcomes following CABG.

Methods: We used the CABG data from two heart centers in northeastern Iran between 2007 and 2016. We included adult patients undergoing CABG surgery. The study outcomes were in-hospital major adverse cardiac and cerebrovascular events (MACCEs), consisting of myocardial infarction (MI), stroke, and cardiovascular death, and postoperative outcomes, including postoperative arrhythmia, acute atrial fibrillation (AF), major bleeding, and acute renal failure (ARF).

Results: Over the course of one decade, 3632 patients, with an average age (standard deviation) of 59.0 (9.8) years, were studied. Of these, 3,331 patients were of non-Turkmen ethnicity, and 301 patients were Turkmens. According to adjusted analysis, ethnicity was not associated with MACCEs (OR: 1.15, 95 % CI: 0.61, 2.16; P=0.663), postoperative arrhythmia (OR: 1.10, 95% CI: 0.78, 1.54; P=0.588), acute AF (OR: 1.17, 95 % CI: 0.83, 1.66; P=0.359), major bleeding (OR: 1.21, 95 % CI: 0.55, 2.67; P=0.636), or ARF (OR: 2.60, 95 % CI: 0.60, 11.75, P=0.224).

Conclusion: This study found that despite ethnic disparity and preoperative differences, Turkmen ethnicity was not associated with in-hospital MACCEs, AF, major bleeding, or ARF after coronary artery bypass.


Cite this article as: Nomali M, Ayati A, Tayebi A, Moghaddam K, Mosallami S, Riahinokandeh G, et al. Ethnic disparities in major adverse cardiac and cerebrovascular events (MACCEs) and postoperative outcomes following coronary artery bypass in Northeastern Iran (2007–2016). Arch Iran Med. 2023;26(10):554-560. doi: 10.34172/aim.2023.81
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Submitted: 22 Feb 2023
Revision: 06 Jul 2023
Accepted: 22 Jul 2023
ePublished: 01 Oct 2023
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