Academy of Medical Sciences of I.R. Iran Archives of Iranian Medicine 1029-2977 22 12 2019 12 01 Relationship of Uterine Fibroids with Lipid Profile, Anthropometric Characteristics, Subcutaneous and Preperitoneal Fat Thickness 716 721 EN Seyedeh Hajar Sharami https://orcid.org/0000-0001-7815-3769 Sima Fallah Arzpeyma https://orcid.org/0000-0003-2470-0434 Maryam Shakiba https://orcid.org/0000-0002-7497-6001 Sina Montazeri Forozan Milani https://orcid.org/0000-0002-0430-6993 Sodabeh Kazemi Seyedeh Fatemeh Dalil Heirati https://orcid.org/0000-0003-2177-0832 Journal Article 2019 06 30 2019 09 18 Background: Uterine fibroids (UFs) are the most common benign tumors of the uterus with an unknown etiology, affecting many women of reproductive age. We aimed to evaluate the association between UFs and anthropometric features, subcutaneous and preperitoneal fat thickness and lipid profile. Methods: This is a case-control study conducted on 212 women who were available in the Al-Zahra specialized referral hospital from March 2018 to March 2019. Study variables including weight, height, waist and hip circumference were measured for all individuals. For patients with UFs, the size, number and location of fibroids were recorded. Also, subcutaneous and preperitoneal fat thicknesses were measured. Finally, the data were analyzed using the SPSS software ver.16.0 Results: The most common complaint was abnormal uterine bleeding (AUB) in both groups. Most of the patients had a body mass index (BMI) of 25–30. There were significant differences between the two groups in terms of age (P = 0.0001) and waist circumference (P = 0.011). Cholesterol levels were much higher in the case group. Only age and low-density lipoprotein-cholesterol (LDL-C) levels in the case group were positively related to developing UFs, such that with advancing aging and increasing levels of LDL-C, the likelihood of experiencing UFs rose by 10% and 1.1%, respectively. Also, there were no significant differences between the two groups regarding in either preperitoneal fat thickness (PFT) or subcutaneous fat thickness (SFT). Conclusion: Our findings suggest that with aging and higher levels of LDL-C, the likelihood of developing UFs rises.