Academy of Medical Sciences of I.R. Iran Archives of Iranian Medicine 1029-2977 21 12 2018 12 01 Comparison of Lipid Ratios to Identify Metabolic Syndrome 572 577 EN Maysam Rezapour Armita Shahesmaeili Ali Hossinzadeh Razieh Zahedi Hamid Najafipour Mohammad Hossein Gozashti Journal Article 2018 03 28 2018 10 28 Background: The objective of this study was to compare various lipid ratios for detection of metabolic syndrome (MetS) in the Iranian general population. Methods: This cross-sectional study involved 5677 subjects aged ≥18 years from the general population in Kerman, Iran. Associations between lipid ratio quartiles and MetS were analyzed using logistic regression models. The areas under receiver operating characteristic (ROC) was calculated to determine the accuracy of lipid ratios in predicting MetS. Results: The adjusted chance of having MetS across quartiles of all lipid ratios had an increasing significant pattern (P < 0.0001). The area under the curves of triglyceride/high-density-lipoprotein-cholesterol (TG/HDL-C) ratio was 0.85 (95% CI = 0.84–0.87) in men and 0.85 (95% CI = 0.84–0.86) in women, of total cholesterol (TC)/HDL-C ratio was 0.79 (95% CI = 0.77–0.81) in men and 0.79 (95% CI = 0.77–0.81) in women and of low-density-lipoprotein cholesterol (LDL-C)/HDL-C ratio was 0.73 (95% CI = 0.71–0.75) in men and 0.74 (95% CI = 0.72–0.76) in women. Conclusion: Our results indicate that the TG/HDL-C Ratio is a better marker than the LDL-C/HDL-C ratio and the TC/HDL-C ratio for identifying MetS in the Iranian population and could be used in clinical practice