Academy of Medical Sciences of I.R. Iran Archives of Iranian Medicine 1029-2977 26 11 2023 11 01 Cardiac Mass and Cerebrovascular Accident as Primary Manifestations of Churg-Strauss Syndrome 662 664 10.34172/aim.2023.97 EN Fariba Abbasi https://orcid.org/0000-0002-5685-3956 Ata Abbasi https://orcid.org/0000-0001-8000-8819 Alireza Rostamzadeh https://orcid.org/0000-0002-9223-3885 Seyede Zohre Banihashemi https://orcid.org/0000-0001-7976-4190 Aliakbar Rajabi https://orcid.org/0000-0002-8032-2741 Journal Article 10.34172/aim.2023.97 2023 02 08 2023 07 03 Churg-Strauss syndrome (CSS), recently named eosinophilic granulomatosis with polyangiitis (EGPA), is a rare form of systemic vasculitis with extravascular granulomas occurring in patients with asthma and tissue eosinophilia. We represent a large left ventricular granuloma, confirmed by histopathologic evaluation, detected as a ventricular mass by echocardiography in a 45-year-old asthmatic male who was admitted for a cerebrovascular accident. Paraclinical and histopathologic findings confirmed the diagnosis of EGPA. As cardiac involvement in patients with EGPA is associated with poor prognosis, routine echocardiographic evaluation of these patients is suggested.