Academy of Medical Sciences of I.R. Iran Archives of Iranian Medicine 1029-2977 24 6 2021 06 01 Acute Acalculous Cholecystitis after Measles 505 507 10.34172/aim.2021.72 EN Emine Füsun Karaşahin https://orcid.org/0000-0003-4145-8117 Ömer Karaşahin https://orcid.org/0000-0002-4245-1534 Journal Article 10.34172/aim.2021.72 2021 01 24 2021 03 15 The recent increase in measles cases will result in a higher incidence of associated complications. Hepatobiliary complications are among rare complications of measles. Here, we present a case of measles complicated by acute acalculous cholecystitis (AAC), which we believe to be only the second case reported in the literature. A 17-year-old woman presented with a maculopapular rash, high fever, sore throat, runny nose, nausea, and generalized body aches. Measles was diagnosed by anti-measles immunoglobulin M (IgM) positivity and a 4-fold increase in immunoglobulin G (IgG) 2 weeks later. On day 5, Murphy’s sign was positive and antibiotic therapy was initiated. Two days later, laparoscopic cholecystectomy was performed due to persistent fever and abdominal pain. The pathology result was consistent with nonspecific cholecystitis. As this case highlights, it should be kept in mind that AAC, which is a rare complication of the multisystem involvement caused by measles, can occur during recovery from the infection.