Academy of Medical Sciences of I.R. Iran Archives of Iranian Medicine 1029-2977 25 5 2022 05 01 Comparison of Unilateral Knee Arthroplasty with High Tibial Osteotomy in Surgical Treatment of Medial Knee Osteoarthritis 324 328 10.34172/aim.2022.53 EN Sinan Zehir https://orcid.org/0000-0003-0644-7826 Ercan Şahin https://orcid.org/0000-0003-0491-9156 Journal Article 10.34172/aim.2022.53 2020 11 12 2021 05 19 Background: High tibial osteotomy (HTO) and unicondylar knee arthroplasty (UKA) are two procedures of choice in moderate medial-sided knee osteoarthritis. In this study, we aimed to compare the outcomes of patients undergoing either unilateral knee arthroplasty or open-wedge HTO both clinically and radiologically. Methods: Clinical records of 105 patients treated surgically with either medial unilateral knee arthroplasty or high tibial osteotomies were reviewed. Fifty-one cases of HTO (group 1) and 54 cases of unicompartmental knee arthroplasty (group 2) were reviewed. Radiographic follow-up data included Kellgren Lawrence index and mechanical alignment measurements using the PACS system. Clinical and functional follow-up data included range of motion degrees and functional assessment scores (Tegner, Lysholm, Knee Society Score and VAS). Results: Mean time of follow-up was 66.10±8.14 months and 65.27±6.95 months for groups 1 and 2, respectively. The HTO group had better radiographic improvement and greater range of motion than the unicompartmental knee arthroplasty group. Despite a significant difference in Lysholm Knee Score and a slight difference in VAS score in favor of HTO, both groups were similar with regard to functional outcomes. Conclusion: Both techniques are satisfactory in terms of functional outcomes about five years after the operation and may be considered in cases of middle-aged medial-sided gonarthrosis (<65 years of age) who do not have additional ligament or compartmental pathology.