Academy of Medical Sciences of I.R. Iran Archives of Iranian Medicine 1029-2977 19 2 2016 02 01 Management of Intravenous Leiomyomatosis of Uterus with Extension to Heart 0 0 EN Kambiz Alizade Godratollah Maddah Amir Hosein Jafarian Arash Khamene Bagheri Reza Jafarzadeh Esfehani Sara Mirzaeian Journal Article Leiomyoma is a benign smooth muscle tumor. Intra-venous extensions of these tumors occur due to tumor growth within uterine vein or lymphatic vessels. In rare cases, intracaval and intracardiac extension can also be seen. Clinical suspicion of this disease should become certain by use of imaging techniques. While the treatment is complete resection of the tumor, one or two-stage surgery can be planned for patient depending on tumor extension and patient’s condition. In this report, a 52-year-old woman with a rare presentation of uterine leiomyoma will be discussed. While the tumor was extended toward right atrium, the patient had nonspecific symptoms. By use of two-stage surgery, separated laparotomy and cardiopulmonary bypass, the tumor was completely removed.