Academy of Medical Sciences of I.R. Iran Archives of Iranian Medicine 1029-2977 14 3 2011 05 01 Helicobacter pylori and its Effects on Human Health and Disease 192 199 EN Payam Sheikhattari Farin Kamangar Mahsa Mohebtash Journal Article H. pylori is now a known cause of gastric and duodenal ulcers, noncardia gastric cancer and gastric MALT lymphoma. In addition, the role of this microorganism in causing or preventing a large number of other diseases has been investigated, some of which include esophageal cancer, functional dyspepsia, gastroesophageal reflux disease, asthma, cardiovascular diseases, iron deficiency anemia and idiopathic thrombotic purpura. This article reviews the evidence for these associations and provides suggestions for further research