Abstract
Background: We aimed to recognize the predictors of long-term major adverse cardiac events (MACE) in the elderly candidates
for elective percutaneous coronary intervention (PCI) at our center.
Methods: In this retrospective cohort study, we reviewed the data of the elderly (age ≥65 years) candidates for elective PCI who
met our study criteria, at Tehran heart center between 2004 and 2013. Demographic, anthropometric, clinical, angiographic,
procedural and follow-up data of the enrolled patients were retrieved from the angiography/PCI databank of our center. The study
characteristics of the patients with or without MACE were compared in a univariable Cox-regression analysis. A multivariable Coxregression
model was applied using variables selected from the univariable model to determine the predictors of MACE.
Results: We reviewed the data of 2772 patients (mean age=70.8±4.7 years, male sex=1726 patients [62.3%]) from which 393
patients (14.4%) developed MACE. In the multivariable regression model, female sex was a protective factor for MACE (hazard
ratio [HR]=0.701; P=0.001), while presence of diabetes mellitus (HR=1.333; P=0.007), family history of coronary artery disease
(CAD) (HR=1.489; P=0.003) and plain balloon angioplasty (HR=1.810; P=0.010) were independent risk factors for MACE.
Conclusion: PCI is a safe and effective method of revascularization in the elderly patients, and some clinical and procedural factors
can predict MACE in this group of patients