Esma Altinel Acoglu
1, Fatma Yazilitas
2, Asuman Gurkan
3, Eyup Sari
1, Saliha Senel
1, Meltem Akcaboy
1*1 Department of Pediatrics, Dr. Sami Ulus Maternity and Children’s Health and Diseases Training and Research Hospital, Ankara, Turkey
2 Department of Pediatric Nephrology/rheumatology, Dr. Sami Ulus Maternity/ Children’s Health and Diseases Training and Research Hospital, Ankara, Turkey
3 Department of Dermatology, Dr. Sami Ulus Maternity and Children’s Health and Diseases Training and Research Hospital, Ankara, Turkey
Abstract
The aim of the presentation of this case is to discuss whether there is an association with eosinophilic granulomatosis with polyangiitis (EGPA) and the use of montelukast, and clarithromycin and to discuss a successful treatment course. A 4-year-old girl with a preceding history of asthma attacks and increased eosinophil counts was admitted. She had been using clarithromycin for five days and montelucast for a month. She was eventually diagnosed with EGPA with detailed examination. Clinicians should remember EGPA in children with asthma and hypereosinophilia. Patients receiving leukotriene receptor antagonists and/or macrolides should be monitored for developing a multisystem disease. Treatment with immunosuppressive agents may be required to ensure a good prognosis.