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Arch Iran Med. 2024;27(11): 639-642.
doi: 10.34172/aim.31235
PMID: 39535001
PMCID: PMC11558605
Scopus ID: 85208952722
  Abstract View: 304
  PDF Download: 294

Case Report

Scalp Lesion as the First Manifestation of Pancreatic Adenocarcinoma, A Very Rare Case

Luis Posado-Domínguez 1,2* ORCID logo, Jonnathan Roldan-Ruiz 1,2* ORCID logo, María Martin-Galache 2, Alejandra Ruiz-Villanueva 3, Maria L Perez-García 4

1 Department of Medical Oncology, University Hospital of Salamanca, Salamanca, Spain
2 Biomedical Research Institute of Salamanca, IBSAL, Salamanca, Spain
3 Department of Dermatology, University Hospital of Salamanca, Salamanca, Spain
4 Department of Internal Medicine, University Hospital of Salamanca, Salamanca, Spain
*Corresponding Authors: Luis Posado-Domínguez, Email: luisposado@usal.es; Jonnathan Roldan Ruiz, Email: jroldanr@saludcastillayleon.es

Abstract

Pancreatic adenocarcinoma is one of the most aggressive tumors. Its diagnosis is usually made in locally advanced or metastatic disease and survival is less than one year. The most frequent sites of metastatic involvement are the liver, peritoneum and lungs. Other organs such as the bones or the brain may be affected to a lesser extent. Cutaneous involvement of pancreatic adenocarcinoma is extremely rare with less than 150 cases reported in the literature since 1960. Most cases with cutaneous involvement involve the periumbilical region, in a lesion known as “Sister Mary Joseph’s Node”. Scalp metastases are very rare and their diagnosis suggests advanced disease and the prognosis will be dismal. It is very important to perform a complete physical examination and a global anamnesis to guide the request for diagnostic tests. Once the diagnosis of pancreatic adenocarcinoma has been made, a global assessment will be necessary, involving different medical specialists, nurses, psychologists and social workers among others. In many cases, supportive care is the mainstay of treatment.

Cite this article as: Posado-Domínguez L, Roldan-Ruiz J, Martin-Galache M, Ruiz-Villanueva A, Perez-García ML. Scalp lesion as the first manifestation of pancreatic adenocarcinoma, a very rare case. Arch Iran Med. 2024;27(11):639-642. doi: 10.34172/aim.31235
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Submitted: 29 Apr 2024
Accepted: 01 Jul 2024
ePublished: 01 Nov 2024
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