Baris Mantoglu
1* 
, Burak Kamburoglu
1 , Ismail Zengin
2 , Kayhan Ozdemir
1 , Ebru Kayra
3 , Emre Gonullu
1 , Fatih Altintoprak
4 , Belma Kocer
4 1 Sakarya University Teaching and Research Hospital Department of General Surgery/ Sakarya, Turkey
2 Bozuyuk State Hospital Department of General Surgery Bilecik, Turkey
3 Sakarya University School of Medicine Department of Pathology Sakarya, Turkey
4 Sakarya University School of Medicine Department of General Surgery/ Sakarya, Turkey
*Corresponding Author: *Corresponding Author: Baris Mantoglu, MD; İstiklal Mh 335 sok Buyapı Diamond sitesi A blok A giriş D15 Serdivan, Sakarya, Turkey. Tel: +90 505 8159379; E-mail: , Email:
barismantoglu@gmail.com.tr
Abstract
Breast cancer is one of the rarest types of cancer in men. Its incidence increases with age, as in women. Neurofibromatosis type 1 is an autosomal dominant genetic disease that predisposes to many cancer types. Neurofibromatosis and breast cancer have been more frequently distinguished and better studied in women. Characteristically, estrogen, progesterone receptors, negative, and overexpression of human epidermal growth factor receptor 2 (HER2) are detected in patients with female neurofibromatosis breast cancers. In cases reported so far, estrogen and progesterone receptors have been evaluated as positive and HER2 negative in male patients. With the high possibility of breast cancer development in female patients with neurofibromatosis at an earlier age, prompt and careful evaluation is required in terms of both examination and radiological imaging. Unfortunately, there are no thorough recommendations for breast cancer follow-up in male patients with neurofibromatosis. Here, we present a breast cancer, which is an uncommon type of cancer in male neurofibromatosis.