Abstract
Background: In 1990, one of the most important strategies of supporting and managing reproductive research focused on
development of research structures. This targeted vision, at the first step, mainly followed through creating research units. The
present paper aims to explore the policies and strategies of medical research centers (MRCs)development, and its achievements
and challenges over the last 25 years.
Methods: Based on expected outcomes of better directions of research activities aligned with the priorities and policies of
research, the Deputy of Research and Technology of Ministry of Health and Medical Education (MOHME), initiated the set up and
development of research units.
Results: During the last 24 years, the number of MRCs has increased from 1 in 1992 to 736 in 2016. The progressive trends of
expansion of the research centers are affected by a complex set of influencing factors. At first steps of program, the process of
establishment and development of research structures followed slow trends in few unstructured primary centers. From 2008 to
2012, a rapid investment in development of research structures in biomedicine fields led to numerous complex challenges in
supervision and management of MRCs (MRCs).
Conclusion: Participatory approach in research centers management, benefiting from all available capacities of research
stakeholders, could be considered as a practical strategy for better management of limitations and achieving targeted goals.