Mohammad Reza Mohammadi
1 
, Seyed Kaveh Hojjat
2,3* , Seyed Ali Mostafavi
1, Ali Khaleghi
1, Zahra Hooshyari
1, Nastaran Ahmadi
4, Faezeh Kaviyani
3, Mina Norozi Khalili
31 Psychiatry and Psychology Research Center, Roozbeh Hospital, Tehran University of Medical Sciences, Tehran, Iran
2 Division of Sleep Medicine, Psychiatry and Behavioral Sciences Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
3 Addiction and Behavioral Sciences Research Center, North Khorasan University of Medical Sciences, Bojnurd, Iran
4 Yazd Cardiovascular Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
*Corresponding Author: *Corresponding Author: Seyed Kaveh Hojjat, MD; Hore-Ameli Street, Ebne-Sina psychiatric hospital, Psychiatry and Behavioral sciences research center, Mashhad, Iran. Tel: +98- 5137002345; Email: , Email:
S.kavehhojjat1@gmail.com
Abstract
Background: This study investigated how the parents’ personality disorders may be related to substance use disorder in children and adolescents.
Methods: The study was a cross-sectional study in which 28,540 children and adolescents (aged 6 to 18 years) and their parents participated between 2015 and 2016. The diagnosis of substance use was made using the Kiddie Schedule for Affective Disorders and Schizophrenia--Present and Lifetime Version (K-SADS-PL) interview and the personality disorders were assessed using Millon Clinical Multiaxial Inventory - Third Edition (MCMI-III). The parents were also surveyed for their personality assessed with MCMI.
Results: The results showed that the paranoid personality disorder in father (odds ratio [OR] = 8.34, 95% CI, P = 0.042) and borderline personality disorder in mother (OR = 4.6, 95% CI, P = 0.049) increase the chance of substance use in children.
Conclusion: The findings suggest that in designing preventive programs for substance use, the personality characteristics of the parents need to be taken into account.