Abrupt Development of Plasma Cell Leukemia in a Patient with Chronic Anemia under Follow-up

Mohamad Reza Farzaneh^*, Ali Moradi, Mohammad Reza Ravanbod, Mohammad Daghbashi

*Corresponding Author: Email: mrfarzaneh@yahoo.com

Abstract

Plasma cell leukemia (PCL) is a very rare and progressive hematologic malignancy with unpleasant prognosis, which present with monoclonal proliferation of plasma cells in peripheral blood. Here we report a 52-year-old female case of PCL which diagnosed by morphology and immunohistochemistery (IHC) study. IHC revealed CD20+/CD38+/CD138+/CD56-/kappa-/lambda+. We diagnose PCL on peripheral blood. IHC can be helpful for prognostic determination.

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