Logo-aim
Arch Iran Med. 2014;17(2): 0.
PMID: 24527973
Scopus ID: 84894245073
  Abstract View: 2773
  PDF Download: 1590

Original Article

Model for End stage Liver Disease (MELD) and Child-Turcotte-Pugh (CTP) scores: Ability to predict mortality and removal from liver transplantation waiting list due to poor medical conditions

Nasim Rahimi-Dehkordi, Keramat Nourijelyani*, Mohsen Nasiri-Tousi, Robabeh Ghodssi-Ghassemabadi, Farid Azmoudeh-Ardalan, Saharnaz Nedjat
*Corresponding Author: Email: nourik@tums.ac.ir

Abstract

BACKGROUND: There are many patients awaiting liver transplantation withonly few donors providing the organ. The Child-Turcotte-Pugh score (CTP) and the Model for End stage Liver Disease (MELD) are the most common scores for prioritizingpatients on waiting lists. In this study, we compared the ability of these scores to predict mortalityor removal from the waiting list due to poor medical conditions.
METHODS: A total of257 patients were included in our study and we observed their status in the waiting list overa 9-month period. MELD and CTP of the patients at the time of listing were calculated. We used both ROC-curve and Area Under the Curve (AUC) to calculate the predictive ability of these scores.
RESULTS: During follow up, 22 patients died and 9 patients were removed from the waiting list due to poor medical conditions. Comparing the predictive ability of CTP and MELD, the AUC for CTP was larger than that of MELD (0.75 versus 0.69; P-value = 0.065). The best cutoff point for discriminating mortality or removal from the waiting list due to severe deterioration is 8 for CTP and 13.67 for MELD. The sensitivity and specificity was 0.74 and 0.67, respectively for CTP and 0.74 and 0.58, respectively for MELD.
CONCLUSION: The CTP score can predict mortality or removal from the liver transplantation waiting list better than the MELD overa 9-month period. However, better improved models need to be developed for prioritization of patients in the waiting list.

First Name
 
Last Name
 
Email Address
 
Comments
 
Security code


Abstract View: 2774

Your browser does not support the canvas element.


PDF Download: 1590

Your browser does not support the canvas element.

ePublished: 01 Feb 2014
EndNote EndNote

(Enw Format - Win & Mac)

BibTeX BibTeX

(Bib Format - Win & Mac)

Bookends Bookends

(Ris Format - Mac only)

EasyBib EasyBib

(Ris Format - Win & Mac)

Medlars Medlars

(Txt Format - Win & Mac)

Mendeley Web Mendeley Web
Mendeley Mendeley

(Ris Format - Win & Mac)

Papers Papers

(Ris Format - Win & Mac)

ProCite ProCite

(Ris Format - Win & Mac)

Reference Manager Reference Manager

(Ris Format - Win only)

Refworks Refworks

(Refworks Format - Win & Mac)

Zotero Zotero

(Ris Format - Firefox Plugin)