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Arch Iran Med. 2020;23(6): 397-402. doi: 10.34172/aim.2020.33

Original Article

Effect of N-acetylcysteine against Vancomycin-Induced Nephrotoxicity: A Randomized Controlled Clinical Trial

Shirinsadat Badri 1,2 ORCID, Rasool Soltani 1 * ORCID, Mina Sayadi 3, Farzin Khorvash 4,5, Mohsen Meidani 4, Shahram Taheri 2

Cited by CrossRef: 8


1- Feng Y, Yang Y, Chen H. Small Molecules as a Source for Acute Kidney Injury Therapy. SSRN Journal. 2021; [Crossref]
2- Bellos I, Pergialiotis V, Perrea D. Kidney biopsy findings in vancomycin-induced acute kidney injury: a pooled analysis. Int Urol Nephrol. 2022;54(1):137 [Crossref]
3- Yuan M, Briscese K, Hong T, Brunetti L. Natural products for the prevention of antibiotic-associated kidney injury. Current Opinion in Toxicology. 2022;32:100363 [Crossref]
4- Magalhães E, Silva B, Aires N, Ribeiro L, Ali A, Cavalcanti M, Nunes J, Sampaio T, de Menezes R, Martins A. (−)-α-Bisabolol as a protective agent against epithelial renal cytotoxicity induced by amphotericin B. Life Sciences. 2022;291:120271 [Crossref]
5- Packialakshmi B, Stewart I, Burmeister D, Chung K, Zhou X. Large animal models for translational research in acute kidney injury. Renal Failure. 2020;42(1):1042 [Crossref]
6- Sadeghi H, Karimizadeh E, Sadeghi H, Panahi kokhdan E, Mansourian M, Abbaszadeh-Goudarzi K, Shokripour M, Asfaram A, Doustimotlagh A, Abdel-Daim M. Protective Effects of Hydroalcoholic Extract of Rosa canina Fruit on Vancomycin-Induced Nephrotoxicity in Rats. Journal of Toxicology. 2021;2021:1 [Crossref]
7- Mosayebi S, Soltani R, Shafiee F, Assarzadeh S, Hakamifard A. Evaluation of the effectiveness of n-acetylcysteine in the prevention of colistin-induced nephrotoxicity: A randomized controlled clinical trial. J Res Pharm Pract. 2021;10(4):159 [Crossref]
8- Alosaimy S, Rybak M, Sakoulas G. Understanding vancomycin nephrotoxicity augmented by β-lactams: a synthesis of endosymbiosis, proximal renal tubule mitochondrial metabolism, and β-lactam chemistry. The Lancet Infectious Diseases. 2024;24(3):e179 [Crossref]
9- Feng Y, Yang Y, Chen H. Small molecules as a source for acute kidney injury therapy. Pharmacology & Therapeutics. 2022;237:108169 [Crossref]


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About Us

A Monthly Peer-Reviewed Medical Journal Published by the Academy of Medical Sciences of the I.R. Iran; Indexed in PubMed/MEDLINE, ISI Web of Science, EMBASE, SCOPUS, CINHAL, PASCAL, CSA, SID, ISSN: Print 1029-2977, Online 1735-3947.The impact factor of Archives of Iranian Medicine according to Journal Citation Reports® (JCR®) 2016 is 1.20.